Irresistible Spicy Southern Chicken Spaghetti Casserole

Name: Irresistible Spicy Southern Chicken Spaghetti Casserole
Prep time: 15 min
Cook time: 4 h
Total time: 4 h 15 min
Yield: 6 servings
Ingredients: 2 cups cooked chicken, shredded; 8 ounces spaghetti, uncooked; 1 can (10.5 ounces) cream of chicken soup; 1 can (14.5 ounces) diced tomatoes with green chilies; 1 cup chicken broth; 1 cup shredded cheese; 1 teaspoon paprika; 1 teaspoon garlic powder; Salt and pepper to taste

Highlighted under: Comfort Food

Savor the comforting fusion of flavors in this Irresistible Spicy Southern Chicken Spaghetti Casserole. This hearty dish combines tender chicken, zesty seasonings, and a creamy sauce, all baked with pasta to create a mouthwatering casserole perfect for family dinners or potlucks. Easy to prepare in your crockpot, it's a deliciously satisfying meal that brings a spicy twist to classic comfort food.

Created by

Georgia Lane

Last updated on 2025-11-27T06:24:33.555Z

This casserole is a delectable blend of spicy and creamy flavors that will keep everyone coming back for more. Perfect for gatherings!

A Flavorful Twist on Comfort Food

Comfort food often reminds us of cherished family gatherings and cozy nights in. This Irresistible Spicy Southern Chicken Spaghetti Casserole takes that traditional comfort and adds a delightful twist with its bold and zesty flavors. By incorporating shredded chicken and a creamy sauce, this dish becomes both filling and satisfying, making it a perfect choice for any occasion.

The unique combination of chicken, spaghetti, and southwestern spices creates a medley of tastes that will delight your palate. With every bite, you'll experience the heartiness of the pasta, the richness of the creamy sauce, and the warming kick from the spices. It’s the ultimate dish for those who appreciate the art of blending flavors in a comforting casserole.

Easy Crockpot Preparation

One of the best features of this casserole recipe is its simplicity and ease of preparation. With just a few steps, you can have a delicious meal ready in your crockpot. By using pre-cooked chicken and uncooked spaghetti, this method allows everything to cook together, infusing the flavors beautifully and ensuring that the pasta absorbs all the tasty goodness.

Set your crockpot in the morning, and by dinner time, you'll have a creamy and flavorful dish waiting for you. This makes it an excellent choice for busy weeknights or when hosting gatherings, as it requires minimal active cooking time, allowing you to spend more time with family and friends.

Versatile Serving Suggestions

This casserole is an incredibly versatile dish that can fit into any meal plan. Serve it as the main attraction at a potluck, alongside a fresh salad or some crusty bread, and watch it disappear within minutes. Alternatively, you can pair it with a simple vegetable side or a light coleslaw for a more balanced meal.

For those who like to entertain, consider adding a variety of toppings when serving. Optional garnishes like fresh herbs, sliced jalapeños, or a dollop of sour cream can add an exciting dimension to the dish. This adds not only to the presentation but also elevates the flavor, making it a crowd-pleaser.

Ingredients

Main Ingredients

2 cups cooked chicken, shredded
8 ounces spaghetti, uncooked
1 can (10.5 ounces) cream of chicken soup
1 can (14.5 ounces) diced tomatoes with green chilies
1 cup chicken broth
1 cup shredded cheese
1 teaspoon paprika
1 teaspoon garlic powder
Salt and pepper to taste

Mix all the ingredients in your crockpot for a delightful meal!

Directions

Prepare the Ingredients

In a large bowl, combine the shredded chicken, uncooked spaghetti, cream of chicken soup, diced tomatoes, chicken broth, and seasonings. Mix well.

Cook the Casserole

Transfer the mixture into your crockpot. Cover and cook on low for 4 hours or until the pasta is tender. Stir occasionally.

Add the Cheese

Before serving, sprinkle the cheese over the top and allow it to melt for 10 minutes.

Serve and Enjoy

Serve hot and enjoy the deliciously spicy flavor of your casserole!

Make sure to savor every bite of this delightful dish!

Nutritional Benefits

This Irresistible Spicy Southern Chicken Spaghetti Casserole is not just a delicious treat; it's also packed with nutritional benefits. Chicken is a fantastic source of lean protein, essential for building and repairing tissues. Combining it with tomatoes and spices provides antioxidants and anti-inflammatory properties, contributing to your overall health.

Moreover, the incorporation of pasta offers energy-boosting carbohydrates, essential for an active lifestyle. By using whole grain spaghetti, you can increase the fiber content, making this casserole even more beneficial. It’s a balance of wholesome ingredients that can fuel your family’s day while indulging their taste buds.

Storing and Reheating Leftovers

If you find yourself with leftovers, storing them properly is key to enjoying the casserole later. Allow the dish to cool completely before transferring it to an airtight container. It can be refrigerated for up to three days or frozen for longer storage. Just make sure to label and date any containers to keep track of freshness.

When you're ready to enjoy the leftovers, reheating can be done easily in the microwave or oven. For the microwave, place a portion in a safe dish and heat in short intervals, stirring until heated through. If using the oven, cover with foil to prevent drying out and reheat at 350°F until warmed throughout.

Experiment with Ingredients

One of the exciting aspects of this casserole is its adaptability. Feel free to experiment with ingredients based on your preferences. You can swap out chicken for turkey or even use a plant-based protein for a vegetarian version. Different types of cheese can also be added to enhance flavor, such as pepper jack for extra spice or mozzarella for creaminess.

Additionally, you can include vegetables like bell peppers, spinach, or zucchini to boost the nutrient content and introduce new textures. The versatility of this recipe allows you to customize it to fit your dietary needs and flavor profiles, making it a staple in your recipe rotation.

Questions About Recipes

→ Can I use other types of pasta?

Yes, feel free to substitute with your favorite pasta shape!

→ How can I make it healthier?

You can use whole grain pasta and low-fat cheese to lighten it up.